Hu CD29 NALE HUTS-21 500ug

• 产品编号：BD-556047      品牌：BD-Pharmingen       原厂货号：556047
• 产品分类：抗体 > 一抗 > 蛋白特异性一抗
• 应用分类：

描述：

Reacts with the 130 kDa integrin β1 subunit, CD29, that is expressed following cell activation as a heterodimeric complex with one of nine
distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. The HUTS-21 β1 epitope is weakly
expressed on resting lymphocytes, but is upregulated by TPA, Ca++ ionophore, or another CD29 antibody, TS2/16. This upregulation is
Mn++ dependent and not supported by other divalent cations such as Ca++ and/or Mg++. The VLA receptors have a broad cellular
distribution and interact with ligands like VCAm-1 and MAdCAM-1 during cell adhesion. They also interact with extra-cellular matrices
including collagen, laminin, fibronectin and others. HUTS-21 antibody enhances adherence of TPA-activated lymphocytes to fibronectin.

原厂资料：

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Store undiluted at 4°C.