Reacts with the macrophage mannose receptor (MR), a membrane glycoprotein of approximately 162 kDa which binds to glycoconjugates
containing mannose, fucose, or N-acetylglucosamine. These carbohydrates are present on the surface of many microorganisms and enable the
macrophage to bind to microorganisms through the MR and internalize them during the process of phagocytosis. Mannose receptors are
expressed on human macrophages and cultured dendritic cells. They are not detected on resting monocytes. Mannose receptor expression is
upregulated on PBMC following 3 day incubation with GM-CSF.
原厂资料:
注意事项:
1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.