Hu CD59 FITC p282 (H19) 100Tst

产品编号：BD-555763 品牌：BD-Pharmingen 原厂货号：555763
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100Tst

运保温度:

Store undiluted at 4°C

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描述：

该抗体与CD59发生反应。CD59是一个19 kDa的糖基磷脂酰肌醇（GPI）锚定的糖蛋白，表达于造血细胞和非造血细胞。由于可与补充活化产物发生相互作用，CD59被称为攻膜复合物抑制因子（MACIF）、同源限制因子（HRF20）、反应性细胞溶解的膜抑制因子（MIRL）和保护因子。它通过结合于C8和C9，阻断攻膜复合物的组装，从而抑制补体的溶细胞活性。CD59还参与自发T细胞/红细胞粘附，与CD2相互作用，并在T-细胞活化中也起到作用。

原厂资料：

Reacts with CD59, a 19 kDa glycosylphosphatidylinositol (GPI)-anchored glycoprotein, expressed on hematopoietic and non-hematopoietic cells. Because of its role in interaction with complement activated products, CD59 has been termed membrane-attack-complex-inhibitory factor (MACIF), homologus restriction factor (HRF20), membrane inhibitor of reactive lysis (MIRL) and protectin. It inhibits the cytolytic activity of complement by binding to C8 and C9, thereby blocking the assembly of the membrane attack complex. CD59 also participates in spontaneous T-cell/erythrocyte adhesion, interacts with CD2 and plays a role in T-cell activation.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.

3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

5.Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.