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Hu CD86 PE-Cy5 IT2.2 100Tst

  • 产品编号:BD-555666      品牌:BD-Pharmingen       原厂货号:555666
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 100Tst
运保温度: Store undiluted at 4°C
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描述:

IT2.2 recognizes a 75 kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells including lymphoid
cells in germinal centers and Epstein-Barr virus transformed B-cell lines. CD86 is the second ligand for CD28 and CTLA-4 and may play an
important role in costimulation of T cells in primary immune response. Competitive binding assays demonstrate that, while both IT2.2 and
FUN-1 (anti-CD86, Cat. No. 555665) recognize the same molecule, they react with different epitopes. IT2.2 blocks costimulation activity of
CD86 in functional studies and blocks binding of human CTLA-4-Ig fusion protein to B70 gene-transfected cells.
 


注意事项:


1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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