Hu CD86 Pure IT2.2 100ug

包装：

100ug

运保温度:

Store undiluted at 4°C.

到货周期：

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描述：

IT2. recognizes a75 kDa cel surface protein, CD86 (B70/B7-2), expresd primarily onmoncytes and activated Bcels including lymphoid

cels ingerminal centrs and Epstein-Bar virus transformed B-cel ines. CD86 isthe scond ligand for CD28 and CTLA-4 and may play n

importan role incostimulation fT cels inprimary imune rsponse. Competive bindg asys demonstrae tha, while both IT2. and

FUN-1 (anti-CD86, Cat. No. 565) recognize the same molecule, they react with difernt epitopes. IT2. blocks costimulation activy of

CD86 infunctional studies and blocks bindg ofhuman CTLA-4Ig fusion protein toB70 gen-transfectd cels.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before

discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C.