Hu CD64 FITC 10.1 100Tst

• 产品编号：BD-555527      品牌：BD-Pharmingen       原厂货号：555527
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

该单克隆抗体与CD64特异性结合。CD64是一种75 kD的I型跨膜糖蛋白，是对gG（FcγRI）的高亲和性受体。 CD64是免疫反应的发展的关键受体，作为IgG3的低亲和力受体和IgG2a的高亲和力受体，在非特异性免疫和适应性免疫的关联中起到双重作用。 CD64介导的内吞作用、吞噬作用、抗体依赖性细胞毒性作用、细胞因子的释放和超氧化物的产生。CD64在巨噬细胞和树突状细胞中大量表达。

原厂资料：

The monoclonal antibody 10.1 reacts with CD64, a 75 kD type I transmembrane glycoprotein that is a high affinity receptor for IgG (FcγRI). CD64, a key receptor in the development of immune responses, has a dual role as a low affinity receptor for IgG3 and high affinity receptor for IgG2a linking innate and adaptive immunities. CD64 mediates endocytosis, phagocytosis, antibody-dependent cellular toxicity, cytokine release and superoxide generation. CD64 is expressed largely on macrophages and dendritic cells.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Source of all serum proteins is from USDA inspected abattoirs located in the United States.

5.Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.