Hu CD3 FITC HIT3a 100Tst

• 产品编号：BD-555339      品牌：BD-Pharmingen       原厂货号：555339
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

该抗体与人 CD3 ε链反应。此ε链是表达于70％-80％的正常人外周血淋巴细胞和60％-85％的胸腺细胞的CD3/ T细胞抗原受体复合物的20-kDa的亚基。研究表明，这种抗体与美洲商陆有丝分裂原偶联使用时，具有促有丝分裂的作用。CD3子抗原识别过程中起到信号转导作用。UCHT1抗体可染色细胞内CD3。另一个克隆HIT3a，仅可染色细胞外CD3。该抗体常用于FACS分析。

原厂资料：

Reacts with the human ε-chain, a 20 kDa subunit of CD3/T cell antigen receptor complex found on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show this antibody to be mitogenic when used in conjuction with pokeweed mitogen. CD3 plays a role in signal transduction during antigen recognition. HIT3a antibody does not stain intracellular CD3 unlike the other CD3 clone, UCHT1.
This antibody is routinely tested by flow cytometric analysis.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Source of all serum proteins is from USDA inspected abattoirs located in the United States.
5. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.