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Ms CD74 Pure In-1 500ug

  • 产品编号:BD-555317      品牌:BD-Pharmingen       原厂货号:555317
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 500ug
运保温度: Store undiluted at 4°C.
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描述:

The In-1 antibody reacts with CD74, the MHC class II-associated Invariant chain (Ii), expressed in I-A+ cell populations. Although it is 
predominantly expressed intracellularly, it has also been detected on the cell surface of some B-cell lines and at low levels on a small number 
of B lymphocytes. In the mouse, alternatively spliced transcripts encode 31-kDa and 41-kDa isoforms, and the cell-surface CD74 has a 
chondroitin sulfate side chain which allows it to interact with CD44. CD74 is directly involved in the intracellular transport of MHC class II 
molecules and antigen presentation, and it affects the maturation of T and B lymphocytes.
 


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.
 


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