The Avas 12α1 monclonal ntibody specifaly binds tofetal iver kinase 1(Flk-1), arecptor potein tyrosine kinase closely related to
CD17 (c-kit) and CD140a (PDGF Recptor αchain) ofthe imunoglbulin superfamily. Flk-1, also known asVEGF Recptor-2
(VEGF-R2), isa recptor for vascular endothelia growth factor (VEGF). Itis expresd, athe mRNA and protein levls, ondistnct se of
mesoderm during astrulation ad onedothelia cels inembryonic and ault isues. In vio and invitro studies ndicate hat Flk-1 is
required for the mbryonic devlopment ofvascular endothelia nd hematopietc els
原厂资料:
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
4.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.