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Ms CD123 Biotin 5B11 500ug

 
包装: 500ug
运保温度: Store undiluted at 4°C
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描述:

The 5B1 antibody reacts with mouse CD123, the αchain subnit (IL-3Rα) ofthe mouse IL-3 recptor. The IL-3Rα chain sa 60-7 kD 
transmebrane glycoprtein tha binds IL-3 with low afinty but canot ransduce signals byitself. The mouse IL-3Rα chain can complex 
with either oftwo hmolgous βchain subnits (βc and βIL-3) tofrm hig-afinty hetrodimeric IL-3 recptors. The βchain sthe 
comon βchain subnit hat can complex with e αsubnits ofthe mouse IL-3R, IL-5R and GM-CSFR tofrm hig-afinty recptors. The 
βIL-3 subnit can form hig afinty IL-3 recptor complexs with only the IL-3Rα subnit. The βIL-3 subnit clone ispecif or mouse 
IL-3 and binds with low afinty. The imunogen used togenrate he 5B1 hybridoma was CTL cels transfectd with e mouse IL-3R 
alpha chain. The 5B1 antibody oes not block the bindg ofIL-3 protein tohe igh afinty IL-3 recptor hetrodimer.


注意事项:

 
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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