Rat CD161a NKR-P1A PE 10/78 200ug

产品编号：BD-555009 品牌：BD-Pharmingen 原厂货号：555009
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

200ug

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The 10/78 antibody reacts with NKR-P1A, a 60-kDa homodimer expressed on all natural killer (NK) cells and a small subset of T

lymphocytes. The 10/78 antibody competes with the previously described 3.2.3 antibody for binding to the antigen. NKR-P1A is a type-II

integral membrane protein with an extracellular C-type lectin domain, which is an NK cell-activating receptor specific for tumor target cells.

Many rat dendritic cells have been shown to express NKR-P1A, and a subpopulation of these cells has cytotoxic activity. NKR-P1A has also

been detected at low levels on peripheral blood monocytes, and its expression is upregulated in IFN-γ-activated monocytes, specifically in a

subpopulation of large monocytes with phagocytic capacity. Furthermore, activated peripheral blood neutrophils may express a low level of

NKR-P1A. In the mouse and rat, three members of the NKR-P1 gene family have been identified; but in the human gene family, a single

NKR-P1 homologue has been discovered and designated Cd161.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

4.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.