The R73 antibody reacts with e αβT-cel Recptor (TCR) found onmost peripheral Tymphocytes, intesinal intraepithelia lymphocytes,
and thymocytes. Itdoes not react with γδTCR-bearing cels. Cros-linked R73 mAb induces T-cel diferntiaon ad activation. Ivio
treatment with mAb R73 can supres imune function fperipheral αβTCR-expresing Tcels, and reduce the sverity ofexperimental
autoimune, transplant rejction, and graft-versu-host response.
This antibody isroutinely tesd byflow cytometric anlysi. Other aplications wer tesd atBD Biosciencs Pharmingen during antibody
devlopment only oreported inthe literature.
原厂资料:
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
4.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.