Ms CD1d FITC 1B1 500ug

• 产品编号：BD-553845      品牌：BD-Pharmingen       原厂货号：553845
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

原厂资料：

The 1B1 antibody reacts with CD1d, a 48-kDa glycoprotein with structural homology to the major histocompatibility complex (MHC) class I molecules. The structure, expression, and functions of CD1 antigens are complex and have been reviewed. mAb 1B1 detects CD1d at varying levels on most types of bone marrow and peripheral leukocytes and on epithelial, dendritic, and lymphoid cells in the thymus. It appears to recognize CD1d only in association with β2m. CD1d has been reported to be expressed by gastrointestinal tract epithelium and in the cytoplasm of hepatocytes as detected viaimmunohistochemical staining of frozen sections with mAb 3C11 (Cat. No. 559871, for the purified antibody), suggesting a possible role for CD1d in mucosal immunity. However, CD1d expression was not detectable, via flow cytometry, on intestinal epithelial cells in studies using the anti-CD1d mAbs 3C11, 1B1, and 9C7. The 1B1 antibody competes with mAb 3C11 in binding to mouse splenocytes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results. 2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. 3.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. 4.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. 5.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.