The UC7-13D5 antibody reacts with the γδ T-cell Receptor (TCR) complex on γδ TCR-expressing T lymphocytes and NK-T cells of all mouse
strains tested. It does not react with the αβ TCR-bearing T cells. In the mouse, cell expressing the γδ TCR are found in the thymus, intestinal
epithelium, epidermis, dermis, pulmonary epithelium, peritoneum, liver, and peripheral lymphoid organs. Plate-bound UC7-13D5 antibody
activates γδ TCR-bearing T cells, and in vivo administration of the mAb depletes peripheral γδ TCR-bearing T cells.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody
development only or reported in the literature.
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Store undiluted at 4°C.