Ms CD16/CD32 Pure 2.4G2 100ug

产品编号：BD-553141 品牌：BD-Pharmingen 原厂货号：553141
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

100ug

运保温度:

Store undiluted at 4° C

到货周期：

登录后查看

标准价：

￥客户可见

会员价：

￥客户可见

积分：

客户可见分

登录之后可加入购物车购买，请您

运费与支付说明：

1.含干冰类产品有运费；

2. 必须现金付款或有信用额度的会员才可以直接发货，否则需要等待现金付款信息。

描述：

2.4G2抗体特异地与鼠标FcγIII和FcγII受体的胞外域的普通非多态性的表位发生反应。还有报道称，2.4G2抗体通过它的Fc结构域结合FcγI受体（CD64）。在体外和体内，2.4G2单抗可阻断免疫球蛋白与FcγIII和FcγII，以及可能的FcγI受体的非抗原特异性的结合。CD16和/或CD32表达于自然杀伤细胞、单核细胞、巨噬细胞、树突细胞（表达水平较低）、枯否细胞、粒细胞、肥大细胞、B淋巴细胞、不成熟的胸腺细胞，及一些活化的成熟的T淋巴细胞。本抗体一般用于流式细胞术分析测试。

原厂资料：

The 2.4G2 antibody reacts specifically with a common nonpolymorphic epitope on the extracellular domains of the mouse FcγIII and FcγII receptors. It has also been reported to bind the FcγI receptor (CD64) via its Fc domain. 2.4G2 mAb blocks non-antigen-specific binding of immunoglobulins to the FcγIII and FcγII, and possibly FcγI, receptors in vitro and in vivo. CD16 and/or CD32 are expressed on natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

注意事项：

1.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
2. Since applications vary, each investigator should titrate the reagent to obtain optimal results.

3.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Store undiluted at 4° C