Ms CD278 NALE 7E.17G9 500ug

• 产品编号：BD-552437      品牌：BD-Pharmingen       原厂货号：552437
• 产品分类：抗体 > 一抗 > 蛋白特异性一抗
• 应用分类：

原厂资料：

The 7E.17G9 antibody reacts with CD278, the Inducible Costimulatory molecule (ICOS), a 47-57 kDa homodimeric glycoprotein of the
CD28 family of costimulatory molecules. ICOS is expressed on subpopulations of CD4-CD8- and CD4+CD8- (but not CD4-CD8+ or
CD4+CD8+) thymocytes, on some T-cell lines, and on small numbers of peripheral leukocytes. It is upregulated on T lymphocytes following
activation via the T-cell receptor. The T-cell activation marker H4 is the same molecule as ICOS. ICOS is a costimulatory receptor, and its
ligand on antigen-presenting cells has been called B7RP-1, GL50, B7h, B7-H2, or LICOS. There is considerable evidence that the interaction
of ICOS with its ligand is involved in the regulation of many, but not all, T-cell-mediated immune responses.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Store undiluted at 4°C .