The 7N4-1 antibody reacts with human IFN-α2b and to a lesser extent with IFN-α7. It does not react with IFN-α1 nor IFN-α4. IFN-α2b is
one of the three variants of IFN-α2 that have been isolated from human cell lines. IFN-α2b is the variant predominantly produced by human
leukocytes. Human IFN-α2b belongs to the IFN-α class of proteins also known as leukocyte interferons. IFN-α comprises a family of related
but distinct proteins with molecular weights ranging from 16-27 kDa with antiviral, antiproliferative and immunomodulatory activities. The
IFN-α family is composed from as many as 14 different genes. The immunogen used to generate the 7N4-1 hybridoma was E. coli-expressed
recombinant human IFN-α2b. This is a neutralizing antibody.
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Store undiluted at 4°C .