Fibroblast growth factor-basic (FGF-b, FGF-2) is a heparin-binding growth factor which belongs to a family of Fibroblast Growth Factors (FGFs). FGF family members share 35-60% amino acid sequence homology and are highly conserved among species. FGF-basic has been isolated from neural, pituitary, adrenal cortex, and placental tissues. Human FGF-basic is a 17.2 kD protein containing 154 amino acids. Other isoforms (22, 22.5, 24 and 34 kDa) have also been reported with distinct intracellular localizations and functions. FGFs are involved in many physiological and pathological processes including embryonic development, neuronal outgrowth, angiogenesis and malignant transformation. FGF-basic is essential for the development and maintenance of vascular integrity during embryogenesis and is also a major angiogenic factor involved in wound healing, cardiovascular disease and tumor neovascularization.
The BioLegend LEGEND MAX™ Human FGF-basic ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody. This kit is specifically designed for the accurate quantitation of human FGF-basic from cell culture supernatant, serum, plasma, and other biological fluids. This kit is analytically validated with ready-to-use reagents.
原厂资料：
Introduction:
Fibroblast growth factor-basic (FGF-b, FGF-2) is a heparin-binding growth factor which belongs to a family of Fibroblast Growth Factors (FGFs). FGF family members share 35-60% amino acid sequence homology and are highly conserved among species. FGF-basic has been isolated from neural, pituitary, adrenal cortex, and placental tissues. Human FGF-basic is a 17.2 kD protein containing 154 amino acids. Other isoforms (22, 22.5, 24 and 34 kDa) have also been reported with distinct intracellular localizations and functions. FGFs are involved in many physiological and pathological processes including embryonic development, neuronal outgrowth, angiogenesis and malignant transformation. FGF-basic is essential for the development and maintenance of vascular integrity during embryogenesis and is also a major angiogenic factor involved in wound healing, cardiovascular disease and tumor neovascularization.
The BioLegend LEGEND MAX™ Human FGF-basic ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody. This kit is specifically designed for the accurate quantitation of human FGF-basic from cell culture supernatant, serum, plasma, and other biological fluids. This kit is analytically validated with ready-to-use reagents.
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