IL-12 is a potent regulator of cell-mediated immune responses that induces IFN-γ production by NK and T cells. It is produced by activated monocytes /macrophages, B lymphocytes, and connective tissue type mast cells as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD and 40 kD subunits. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+, and CD8+ cells and induces the development of IFN-γ producing Th1 cells.
BioLegend’s LEGEND MAX™ Human IL-12 (p70) ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody.This kit is specifically designed for the accurate quantitation of human IL-12 (p70) from cell culture supernatant, serum, plasma and other biological fluids. This kit is analytically validated with ready-to-use reagents.
原厂资料:
Introduction:
IL-12 is a potent regulator of cell-mediated immune responses that induces IFN-γ production by NK and T cells. It is produced by activated monocytes /macrophages, B lymphocytes, and connective tissue type mast cells as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD and 40 kD subunits. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+, and CD8+ cells and induces the development of IFN-γ producing Th1 cells.
BioLegend’s LEGEND MAX™ Human IL-12 (p70) ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a capture antibody.This kit is specifically designed for the accurate quantitation of human IL-12 (p70) from cell culture supernatant, serum, plasma and other biological fluids. This kit is analytically validated with ready-to-use reagents.