Purified Anti-human DR5 (TRAIL-R2, CD262) Antibody

产品编号：B307402 品牌：Biolegend 原厂货号：307402
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

100 μg

运保温度:

4°C

到货周期：

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描述：

DR5 is 55 kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon-α, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.