Ambion® formamide has been deionized, is nuclease-free, and comes packaged as a liquid in an amber glass bottle under argon. Supplied in 5 bottles containing 500 g each. Formamide lowers the melting temperature of nucleic acid duplexes and is widely used in applications such as Southern and northern blotting, nuclease protection assays, S1 mapping, and in situ hybridization. For critical applications, it is recommended that the formamide from previously opened bottles be deionized before use. Appearance: Clear, colorless Molecular Weight: 45.04 Purity: >99.0% Quality Control: Thoroughly tested for contaminating nonspecific endonuclease, exonuclease, and RNase activity.