AHP393 recognises the human ATM protein, a 350kD polypeptide that is the product of the ATM gene. The ATM gene is defective in Ataxia telangiectasia.
ATM protein is expressed within the nucleus of all normal cells, and is thought to be important in detection of DNA damage.
The antiserum has been termed ATM.V. in relevant publications.
Species Cross-Reactivity
Target Species
Cross Reactivity
Mouse
Yes
Primate
Yes
Rat
Yes
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
ELISA
Flow Cytometry
Immunohistology - Frozen
Immunohistology - Paraffin
Immunoprecipitation
Western Blotting
1/500 - 1/1000
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Storage
Store at +4oC or at -20oC if preferred.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.
Antiserum Preparation
Antisera to ATM were raised by repeated immunisation of rabbits with highly purified antigen.
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