AHP1929 recognises propoxyphene, a synthetic opiate with mild analgesic properties, and its metabolite norpropoxyphene. Propoxyphene is sometimes combined with paracetamol or aspirin. It is particularly used for patients who cannot easily metabolise codeine. The drug is prone to abuse and when associated with other drugs or alcohol can be very toxic, causing a large number of fatalities. The therapeutic index of the drug is relatively small, meaning that even small overdosing can be fatal. Since the drug also has limited effectiveness, its use is decreasing in several countries. Norpropoxyphene is responsible for many of the side effects and may accumulate in the body since it has a very long half-life.
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
ELISA
6.8ug/ml -
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
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