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JNK1/JNK2 ANTIBODY 100 UG BIOSOURCE (TM)

 
包装:
运保温度: 4° C in the dark.
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描述:

Details
Tested species reactivity Human , Mouse , Rat
Host / Isotype Mouse / IgG1, kappa
Class Monoclonal
Type Antibody
Clone 279Q38
Immunogen Recombinant fragment of human JNK1-alpha-1 expressed in E. coli.
Conjugate Unconjugated
Form Liquid
Purification purified
Storage buffer PBS, pH 7.2, with 1% BSA
Contains 0.1% sodium azide
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Tested Applications Dilution *
Immunohistochemistry (Paraffin) (IHC (P)) 1:10-1:100
Western Blot (WB) Assay Dependent

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Background/Target Information

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.

 


注意事项:

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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