Raised against a fusion protein containing amino acid residues 25-130 of the N-terminal region of rat brain 2C subunit; this antibody recognizes the 140,000-dalton 2C subunit, as well as the 180,000-dalton 2A and 2B subunits from rat, mouse or human.
Conjugate
Unconjugated
Form
Lyophilized
Purification
IgG fraction
Storage buffer
PBS
Contains
no preservative
Storage Conditions
-20°C
Tested Applications
Dilution *
Western Blot (WB)
Assay Dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
原厂资料:
注意事项:
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.