Raised against a fusion protein containing amino acid residues 25-130 of the N-terminal region of rat brain 2C subunit; this antibody recognizes the 140,000-dalton 2C subunit, as well as the 180,000-dalton 2A and 2B subunits from rat, mouse or human.
Conjugate
Unconjugated
Form
Lyophilized
Purification
IgG fraction
Storage buffer
PBS
Contains
no preservative
Storage Conditions
-20°C
Tested Applications
Dilution *
Immunohistochemistry (IHC)
Assay Dependent
Western Blot (WB)
Assay Dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
原厂资料:
注意事项:
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.