Full length native Human Cytochrome C oxidase subunit II
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/ml
Purification
purified
Storage buffer
HEPES buffered saline
Contains
0.02% sodium azide
Storage Conditions
4° C, do not freeze
Tested Applications
Dilution *
Immunocytochemistry (ICC)
5-10µg/ml
Western Blot (WB)
1µg/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Cytochrome c oxidase is the fourth complex in the respiratory chain and is responsible for catalyzing the conversion of O2 to H2O. Subunit 2 of the cytochrome c oxidase complex combines with two other subunits (1 and 3) to form a core protein structure that performs many functions of the enzyme. The metallic copper center of this subunit transfers electrons to the heme center of subunit 1, which results in the movement of electrons from cytochrome c to the heme A3 and copper B metallic center of complex IV. Defects in subunit 2 of cytochrome c oxidase can result in COX deficiency, which causes a wide range of symptoms from local myopathy to multiple system pathologies that begin between infancy and adulthood. Abnormalities in this subunit are also associated with tumor development.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
京公网安备11010802025653 版权所有：北京逸优科技有限公司
