The aromatic amine of APTS (8-aminopyrene-1,3,6-trisulfonic acid, trisodium salt) can be reversibly coupled to aldehydes and ketones to form a Schiff base - which can be reduced to a stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3) to form new biotinylated probes.
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For Research Use Only. Not for use in diagnostic procedures.