The Wizard® SV Genomic DNA Purification System provides a fast, simple technique to purify intact DNA from mouse tails, tissues and cultured cells in as little as 20 minutes, depending on the number of samples processed. For this system, either a spin or vacuum ("SV") purification protocol can be used. Up to 20mg of tissue or between 1 × 104and 5 × 106tissue culture cells can be processed per purification. Genomic DNA isolated with this system is of high quality and serves as an excellent template for agarose gel analysis, restriction enzyme digestion and PCR analysis.