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ANTI-EP300 HU BIOT FAB-730044 EACH

 
包装: EACH
运保温度: -20°C
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描述:

Details
Tested species reactivity Human
Published species reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen 1038-1161 of 2414 of EP300 Protein.
Conjugate Biotin
Form Liquid
Concentration 0.5 mg/ml
Purification Affinity chromatography
Storage buffer PBS
Contains 0.09% sodium azide
Storage Conditions Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Tested Applications Dilution *
Immunoprecipitation (IP) Assay Dependent

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

Published Applications  
Immunoprecipitation (IP) See 1 publications below

Background/Target Information

EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.

 


注意事项:

For Research Use Only. Not for use in diagnostic procedures. 
 


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