Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Tested Applications
Dilution *
Flow Cytometry (Flow)
3-5 µg x 10^6 cells
Immunocytochemistry (ICC)
2µg/ml
Immunofluorescence (IF)
1:250
Immunoprecipitation (IP)
2 ug
Western Blot (WB)
1:2000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
730018 has successfully been used to detect CBX3 in mouse, human and rat.
730018 has been successfully used in western blotting and immunofluorescence to detect CBX3.
Background/Target Information
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
原厂资料:
注意事项:
For Research Use Only. Not for use in diagnostic procedures.