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RABBIT ANTI-CONNEXIN 30 100 UG

 
包装:
运保温度: -20°C
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描述:

Details
Tested species reactivity Human , Mouse , Rat , Cat
Published species reactivity Rat , Human , Mouse , Chicken
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthetic peptide derived from the unique C-terminus of the mouse Connexin 30 protein
Conjugate Unconjugated
Form Liquid
Concentration 0.25 mg/ml
Purification Antigen affinity chromatography
Storage buffer PBS, pH 7.4
Contains 0.1% sodium azide
Storage Conditions -20°C

Tested Applications Dilution *
ELISA (ELISA) Assay Dependent
Immunocytochemistry (ICC) 1:100-1:500
Immunofluorescence (IF) 1:100-1:500
Immunohistochemistry (Frozen) (IHC (F)) Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P)) 1:20-1:200
Western Blot (WB) 1-2 µg/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

Published Applications  
Immunohistochemistry (IHC) See 2 publications below
Immunocytochemistry (ICC) See 1 publications below
Western Blot (WB) See 1 publications below
Immunohistochemistry (Frozen) (IHC (F)) See 2 publications below

Background/Target Information

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.

 


注意事项:


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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