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GLUCAGON OLIGO AB-710316 EACH

 
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运保温度: -20°C
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描述:

 

Details
Tested species reactivity Human , Primate
Host / Isotype Rabbit / IgG
Class Oligoclonal
Type Antibody
Immunogen Peptide corresponding to amino acids 53–81 of human Glucagon
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/ml
Purification Protein A
Storage buffer PBS
Preservative 0.09% sodium azide
Storage Conditions Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Tested Applications Dilution *
Western Blot (WB) 2-3 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Product Specific Information

This antibody is predicted to react with mouse, rat, rabbit and porcine based on sequence homology.

ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with Protein A.

ABfinity™ oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.

Background/Target Information

Glucagon is a peptide hormone secreted by alpha cells in the Islet of Langerhans of the pancreas. The peptide is synthesized as a 180 amino acid precursor which is converted to glucagon by prohormone convertase 2 (PC2). The primary role of glucagon is in gluconeogenesis and glycogenolysis. It stimulates the release of glucose by converting glycogen in liver, and also maintains glucose homeostasis in coordination with insulin.

 


注意事项:


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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