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PHOSPHO-STAT1 (TYR701) ANTIBOD 100 UG

 
包装:
运保温度: -20°C
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描述:

Details
Tested species reactivity Human , Mouse
Host / Isotype Rabbit / IgG
Class Monoclonal
Type Antibody
Clone 15H13L67
Immunogen A peptide corresponding to amino acids 697-706 of P42224.
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/ml
Purification Protein A
Storage buffer PBS
Preservative 0.09% sodium azide
Storage Conditions Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Tested Applications Dilution *
Immunocytochemistry (ICC) 0.5-2 ug/ml
Immunofluorescence (IF) 0.5-2 ug/ml
Immunohistochemistry (Paraffin) (IHC (P)) 1:10-1:100
Western Blot (WB) 0.5-2 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Product Specific Information

This antibody is predicted to react with orangutan, Macaque, bovine, porcine, ovine, elk, bat, Xenopus, mouse, rat, chicken and salmon based on sequence homology.

ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale, and purified with Protein A.

ABfinity™ monoclonal antibodies resemble rabbit monoclonals isolated from serum or produced by hybridomas, but demonstrate greater specificity and sensitivity. Because ABfinity™ recombinant antibodies are derived from cloned DNA sequences of the heavy and light antibody chains, they are not susceptible to cell-line drift or lot-to-lot variation, thus allowing for peak specificity and performance.

Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.

Background/Target Information

STAT1 (also known as signal transducers and activators of transcription) is a member of the STAT family of transcription factors. STAT proteins undergo phosphorylation in response to cytokines and growth factors and are translocated to the nucleus. STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6. The protein is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. The STAT1 gene is located on chromosome 2.

 


注意事项:

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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