Tau proteins are proteins that stabilize microtubules by interacting with tubulin. They are abundant in neurons in the central nervous system and are less common elsewhere. When tau proteins are defective and no longer stabilize microtubules properly, this can result in dementias, such as Alzheimer's disease.
6242-0206 reacts with Tau in both the phosphorylated and non-phosphorylated form. It does not react with other microtubule associated proteins or tubulin.
This antibody recognises an epitope between amino acids 95 - 108 of bovine Tau.
Species Cross-Reactivity
Target Species
Cross Reactivity
Chicken
Yes
Human
Yes
Monkey
Yes
Mouse
No
Rat
No
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
Immunohistology - Frozen
Immunohistology - Paraffin
Western Blotting
1/250 - 1/1000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
京公网安备11010802025653 版权所有：北京逸优科技有限公司
