Description: The 31A1067 antibody reacts with mouse and human active and pro-caspase 3. The gene for caspase-3, also known as Yama, CPP32, and apopain, codes for a 32 kDa protein. Caspase-3 is activated by cleavage events at Asp-28/Ser-29 (between N-terminal pro-domain) and Asp-175/Ser-176 (between large and small subunits) to generate a large subunit of 17 kDa and a small subunit of 12 kDa. The 31A1067l antibody was generated against recombinant protein of full-length human caspase-3. The antibody was selected with staurosporine-induced apoptotic HeLa cell lysate.
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