Fibroblast growth factor receptor 1 (FGFR1), recombinant mouse protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.
Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..
This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Glu 376) of mouse FGFR1 isoform 1 (P16092-1) fused to the Fc region of human IgG1 at the C-terminus.
Activity: Measured by its ability to inhibit FGF1-dependent proliferation of BABL/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.1-0.6 ng/mL.
Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.
Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.
Expiration Date: Expires one year from date of receipt when stored as instructed.
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注意事项:
For Research Use Only. Not for use in diagnostic procedures.