Raised against the region of the histone H4 containing the trimethylated lysine 20 (or [K20me3]), using a KLH-conjugated synthetic peptide.
Conjugate
Unconjugated
Form
Frozen
Concentration
Lot-Specific
Storage buffer
whole serum
Preservative
<0.1% sodium azide
Storage Conditions
-20° C, Avoid Freeze/Thaw Cycles
Tested Applications
Dilution *
ChIP assay (ChIP)
1:100
ELISA (ELISA)
1:700
Western Blot (WB)
1:750
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Background/Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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