Cattle , Mollusca , Zebra fish ,Nematode , Human , Mouse , Rat
Published species reactivity
Human , Mouse
Host / Isotype
Mouse / IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1D6E1A8
Immunogen
Human Complex IV subunit I
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/ml
Purification
purified
Storage buffer
HEPES buffered saline
Preservative
0.02% sodium azide
Storage Conditions
4° C, do not freeze
Tested Applications
Dilution *
Western Blot (WB)
1.0 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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