* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Background/Target Information
Porin belongs to the eukaryotic mitochondrial porin family of voltage dependent anion channels which allow the transport of adenine nucleotides and other metabolites throught the outer mitochondrial membrane. The conformation of the protein is regulated by membrane potential, which affects its divalent metal ion selectivity. Porin is also involved in mitochondrial apoptosis, forming permeability transition pore complexes (PTPC) in association with adenine nucleotide transporter, and cyclophilin D, leading to release of apoptogenic factors that activate caspases and initiate cell death.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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