Mouse , Dog , Horse , Human ,Porcine , Rat , Primate , Cattle
Host / Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
35C1
Immunogen
Recombinant protein derived from the full length of human Aurora A Kinase protein
Conjugate
Unconjugated
Form
Frozen
Concentration
0.5 mg/ml
Purification
Protein A
Storage buffer
PBS, pH 7.4
Preservative
0.1% sodium azide
Storage Conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tested Applications
Dilution *
Immunocytochemistry (ICC)
1-2µg/mL
Immunofluorescence (IF)
1-2µg/mL
Immunoprecipitation (IP)
5 ug
Western Blot (WB)
1-3 µg/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Background/Target Information
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
原厂资料：
注意事项：
For Research Use Only. Not for use in diagnostic procedures.
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