ANTI-M CD8A 53-6.7 PERCPCYN5.5 25UG

产品编号：45-0081-80 品牌：invitrogen 原厂货号：45-0081-80
产品分类：抗体 > 一抗 > 染料标记抗体
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包装：

运保温度:

2-8℃

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描述：

Description: The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.