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GSK3 ALPHA/BETA ANTIBODY 100 UG BIOSOURCE (TM)

 
包装:
运保温度: -80°C
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描述:

Details
Tested species reactivity Rat , Human , Mouse
Published species reactivity Human , Mouse
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone 21A
Immunogen The antibody was produced in mouse against a recombinant Xenopus laevis protein
Conjugate Unconjugated
Form Liquid
Purification Protein G
Storage buffer PBS, pH 7.4
Preservative no preservative
Storage Conditions -80°C
Tested Applications Dilution *
Functional Assay (FN) Assay Dependent
Immunoprecipitation (IP) 5-10 ug
Western Blot (WB) 0.5-1.0 ug/ml

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

Published Applications  
Western Blot (WB) See 5 publications below

Background/Target Information

Glycogen synthase kinase-3 beta (GSK3 beta) belongs to the subfamily of glycogen synthase kinases, that play a central role in energy metabolism, neuronal cell development, and body pattern formation. GSK3 has alpha and beta isoforms (51 kDa and 47 kDa respectively), that are functionally dissimilar. GSK3 beta plays a role in insulin and Wnt signaling, and is inhibited following the extracellular signaling events.

 


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