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ANGIOPOIETIN 2 ANTIBODY 100 UG

 
包装:
运保温度: -20°C
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描述:

 

Details
Tested species reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide derived from the N-terminal region of the human, gorilla, and orangutan angiogenin protein, which differs from mouse by one amino acid
Conjugate Unconjugated
Form Liquid
Concentration 0.25 mg/ml
Purification Antigen affinity chromatography
Storage buffer PBS, pH 7.4
Preservative 0.1% sodium azide
Storage Conditions -20°C
Tested Applications Dilution *
Western Blot (WB) Assay Dependent

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Background/Target Information

Angiopoietin 2 and angiopoietin 1 have an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain. The coiled coil domains mediate ligand homo-oligomerization and the fibrinogen-like domains mediate ligand activity. Recombinant human angiopoietin 2 has a molecular mass of approximately 66 kDa in SDS-PAGE under reducing and non-reducing conditions. Angiopoietin 2 probably acts as a natural antagonist for Ang1 and Tie2 both in vivo and in vitro. In adult mice and humans, angiopoietin 2 is expressed at sites of vascular remodeling.

 


注意事项:


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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