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RABBIT X OCCLUDIN (C-TERM) 100 UG

 
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运保温度: -20°C
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描述:

 

Details
Tested species reactivity Dog , Rat , Human , Mouse
Published species reactivity Rat , Human , Mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide derived from the C-terminal region of the human occludin protein
Conjugate Unconjugated
Form Liquid
Concentration 0.25 mg/ml
Purification Antigen affinity chromatography
Storage buffer PBS, pH 7.4
Preservative 0.1% sodium azide
Storage Conditions -20°C
Tested Applications Dilution *
Immunocytochemistry (ICC) 1µg/mL
Immunofluorescence (IF) 1µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) 1:10-1:100
Western Blot (WB) Assay Dependent

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

Published Applications  
Western Blot (WB) See 3 publications below
Immunohistochemistry (Frozen) (IHC (F)) See 1 publications below
Immunohistochemistry (IHC) See 2 publications below

Background/Target Information

Occludin is a 65 kDa protein that can exist in a variety of phosphorylated forms, ranging up to approximately 82 kDa. This phosphorylation is thought to be involved in regulating both the localization and the function of occludin. Polyunsaturated fatty acids are known to up-regulate occludin expression, increasing the transendothelial cell resistance and reducing the cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly and continuously expressed at cell-cell contact sites, whereas non-neural tissues show lower expression and discontinuous distribution.

 


注意事项:


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
 


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