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PHOSPHO-NMDAR2B (TYR1472) ANTI 100 UL

 
包装:
运保温度: -20°C
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描述:

Details
Tested species reactivity Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphorylated Tyr1472 of rat NMDA receptor, NR2B subunit.
Conjugate Unconjugated
Form Liquid
Purification Affinity chromatography
Storage buffer 0.01M HEPES, pH 7.5, with 100µg/ml BSA, 50% glycerol, 0.15M NaCl
Preservative no preservative
Storage Conditions -20°C
Tested Applications Dilution *
Western Blot (WB) 1:1000

* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

 

Background/Target Information

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

 


注意事项:

 
For Research Use Only. Not for use in diagnostic procedures. 
 


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