IgG (Immunoglobulin G) is the most abundant Ig isotype in serum and makes up approximately 80% of all serum Immunoglobulins. In humans, there are four subclasses of IgG with highest serum concentrations of IgG1 followed by IgG2, IgG3 and IgG4. The IgG molecule consists of two heavy and two lights chains (κ and λ) resulting in a molecule with two arms for antigen binding. High levels of IgG antibodies are induced following the initial IgM response in a typical immune response to antigens.
Application guide:
Monoclonal antibodies to human IgG
- for use in ELISpot
capture
MT91/145; purified
detection
MT78/145; biotinylated
- for use in ELISA
capture
MT145; purified
detection
MT78; ALP conjugated
- for use in e.g. antigen-specific ELISA
detection
MT78; ALP conjugated
detection
MT78/145; biotinylated
Mouse monoclonal antibodies to human IgG, clones MT78/145.
Suitable as detection antibodies in ELISpot in combination with purified mAbs MT91/145 as capture antibodies (product code 3850-3).