The main normal function of IgE (Immunoglobulin E) is believed to be in the protection against parasitic infestation. However, IgE is also associated with allergy and allergen-specific IgE antibodies may trigger allergic reactions in the presence of the proper allergen. IgE is normally found in low amounts in serum/plasma but is significantly increased in allergic individuals and the detection of allergen-specific IgE serves as the basis for many in vitro assays for specific diagnosis of allergy.
Application guide:
Monoclonal antibodies to human IgE
- for use in ELISpot (total IgE)
capture
mAb 107; purified
detection
mAbs 107/182/101; biotinylated
- for use in ELISA (total IgE)
capture
mAb 107; purified
detection
mAb 182; biotinylated
- for use in e.g. antigen-specific IgE ELISA
mAbs 107/182/101; purified
mAbs 107/182/101; biotinylated
Mouse monoclonal antibody to human IgE, clone 182. Suitable as detection antibody in ELISA (in combination with clone 107, code 3810-3). The determination of IgE in human serum/plasma samples requires the use of ELISA diluent (code: 3652-D2) for dilution of samples and detection antibody.
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