The main normal function of IgE (Immunoglobulin E) is believed to be in the protection against parasitic infestation. However, IgE is also associated with allergy and allergen-specific IgE antibodies may trigger allergic reactions in the presence of the proper allergen. IgE is normally found in low amounts in serum/plasma but is significantly increased in allergic individuals and the detection of allergen specific IgE serves as the basis for many in vitro assays for specific diagnosis of allergy.
ELISpot PLUS kit for the detection of total human IgE.
This complete kit contains 4 ELISpot plates with PVDF membrane, monoclonal capture antibody, monoclonal biotinylated detection antibodies, Streptavidin-ALP, B-cell activators (anti-CD40 mAb and recombinant human IL-4) and TMB substrate.
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