The main normal function of IgE (Immunoglobulin E) is believed to be in the protection against parasitic infestation. However, IgE is also associated with allergy and allergen-specific IgE antibodies may trigger allergic reactions in the presence of the proper allergen. IgE is normally found in low amounts in serum/plasma but is significantly increased in allergic individuals and the detection of allergen-specific IgE serves as the basis for many in vitro assays for specific diagnosis of allergy.
Application guide:
Monoclonal antibodies to human IgE
- for use in ELISpot (total IgE)
capture
mAb 107; purified
detection
mAbs 107/182/101; biotinylated
- for use in ELISA (total IgE)
capture
mAb 107; purified
detection
mAb 182; biotinylated
- for use in e.g. antigen-specific IgE ELISA
mAbs 107/182/101; purified
mAbs 107/182/101; biotinylated
Please check our different ELISA kits for the detection of total human IgE below. All kits include purified human IgE as a standard which is calibrated against an international standard (NIBSC).
ELISA kit for quantitative determination of total human IgE in plasma/serum samples and cell culture supernatant. The kit contains capture mAb, biotinylated detection mAb, streptavidin-enzyme conjugate ALP and purified human IgE as a standard which is calibrated against an international standard (NIBSC). The determination of IgE in human serum/plasma samples by this kit requires the use of ELISA diluent (code: 3652-D2) for dilution of samples, standard and detection antibody.
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